Open Call – Wellcome Leap – Delta Tissue Program

Apr 22, 2021 | Awards & Funding, Research

To: All Divisional Faculty and Researchers
From: The Office of Research & Office of Corporate and Foundations Relations
Subject: Funding Opportunity

The Office of Foundations Relations is pleased to share this open call for funding from the Wellcome Leap Program.  Please follow the links below for more information.

UCSC Contact:
Funder: Wellcome Leap
OpportunityDelta Tissue Program
Deadline: May 17, 2021


We know that infectious and noncommunicable diseases act at the levels of molecules, cells and tissues, so at least part of the solution resides in measuring and understanding their states. We need a new platform – a ‘tissue time machine’ – that can profile tissue states and predict transitions between states (‘Delta Tissue’ or ‘ΔT’). The platform would provide quantitative, multi-scale, multi-modal information sufficient to build integrated prediction models of key cell and tissue states and transitions.

 Platform Demonstration Areas. To demonstrate and validate the ‘tissue time machine’, we have chosen to develop, test, and validate our platform in biomedical contexts that are as broad as possible: an infectious disease, tuberculosis (TB), and two different cancers, triple-negative breast cancer (TNBC) and glioblastoma multiforme (GBM). Each represents a current, unmet biomedical challenge and features a complex, dynamic set of cell and tissue states and transitions.

Please read the full program announcement to better understand the program goals.

 Funding Level

  • Award amounts will be dependent on specific proposals and work selected for funding.
  • Full direct and government-certified indirect costs appropriate to the execution of the research, are eligible.
  • We are soliciting abstracts and proposals for work over 3 years (with a potential additional one-year option).


Performers from universities and research institutions: small, medium and large companies (including venture-backed); and government or non-profit research organizations are invited to propose.


  • May 17, 2021           Abstract due
  • June 1, 2021             Feedback on abstract
  • July 1, 2021              If invited, proposal due
  • July 30, 2021            Proposal decisions

Special Instructions

Please promptly submit your proposal intake form prior to UCSC’s Internal Institutional Deadlines. For proposal support, or for any questions about institutional requirements, please send requests and questions to the research development team at A proposal development specialist will field your requests.

Call sent: April 19, 2021

The Office of Foundation Relations is a unit of University Relations. The FR team creates and maintains mutually beneficial, long-term relationships with private organizations, matching grant initiatives with educational and research programs and centers. FR supports faculty and staff to identify and approach these and other private foundations and corporations for funding, to assist in strategic positioning of the grant application, and to facilitate funder campus visits.

For a list of recent funding opportunities, please visit the FR website.  FR Calls for Funding

If you have any questions or comments, please contact