The Office of Foundations Relations is pleased to share this open call for funding from the Chan Zuckerberg Initiative.
UCSC Contact: Samantha Forde | forde@ucsc.edu
Funder: Chan Zuckerberg Initiative (CZI)
Program: Measuring Metabolism Across Scales
Overview
The Chan Zuckerberg Initiative (CZI) seeks to support two-year collaborative research projects focused on measuring metabolism across organelles and cells. This Request for Applications (RFA) aims to accelerate innovative discoveries in metabolism and metabolic physiology in health and disease.
Potential areas within the scope of this RFA include, but are not limited to:
- Profiling organelles and cells to understand their heterogeneity and metabolic regulation in maintaining homeostasis;
- Using metabolic rewiring to study the state and fate of specialized cells (e.g., immune cells, adipocytes, neurons, hepatocytes, etc.) programmed by metabolic processes;
- Mechanistic studies of the function and dysfunction of metabolism at the systems physiology level and provide a framework for understanding the molecular and cellular basis of metabolic diseases;
- Studying molecular level metabolite-protein interactions at scale with high sensitivity and selectivity;
- Developing techniques for metabolic tracing to help identify the origin and fate of metabolites and their contribution to cellular processes and interactions; and
- Establishing metabolomics and/or proteomics methodologies to enable high-quality spatial biomolecular analysis of individual organelles and cells.
Funding Levels
- Applications for two types of grants are welcome:
- Expanded Projects: up to $500,000 in total cost
- Focused Projects: up to $250,000 in total cost
- All project awards will be for a 24-month duration.
Eligibility
- Early-career investigators are strongly encouraged to apply as Coordinating PIs and Co-PIs.
- At least one Principal Investigator of the team must have expertise in metabolism or related field.
- Teams may include a total of three PIs. Each application must have one Coordinating PI.
Timeline
- June 1, 2023 Application due (5 P.M. Pacific Time)
- Mid-October 2023 Earliest notification of decisions
- December 1, 2023 Expected start date
Special Instructions
Please submit a proposal intake form prior to UCSC’s internal Institutional Deadlines. Please let Foundation Relations (cfr@ucsc.edu) know if you are interested in applying. For support developing your proposal, please contact the Research Development Specialist assigned to your unit or send a request to resdev@ucsc.edu.
The Office of Foundation Relations is a unit of University Relations. The FR team creates and maintains mutually beneficial, long-term relationships with private organizations, matching grant initiatives with educational and research programs and centers. FR supports faculty and staff to identify and approach these and other private foundations and corporations for funding, to assist in strategic positioning of the grant application, and to facilitate funder campus visits.
For a list of recent funding opportunities, please visit the FR website. FR Calls for Funding